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Biotech: Cell processing robot for medical applications
The importance of developing methods in which certain materials can be introduced into a group of cells has been gaining considerable attention. Owing to safety concerns, the development of a high performance nonbiological method has been expected for clinical application. We applied the oxidative perforation to the microinjection method and found that the injection of a functional dye, an antibody, and mRNA to the cells resulted in almost 100% survival. In the recent study, we extended the perforation process in a large number of cells. A nanobrush- shaped soft-polymer sheets formed by the nanoimprinting, which contained a clinically applicable photosensitizer, are used as the cell membrane perforator. Moreover, we could automate the process by the robotics technology for the high-throughput operation.
Cell Processing Robot
Robotics: Living-body-mimicking Robotics
Our cell processing technology originally comes from the research on “Neural interface”: a device that acts as an information mediator between the neuron cells and artificial instruments. To evaluate neural interface for controlling human prosthesis devices e.g. artificial limbs, we are preparing a proto-type “artificial body” for the interface implanted rat. As a result of our first trial, we could develop new linkage mechanisms and the robot which equipped the mechanism could carry out the various walks including side stepping with high speed, by swinging the legs. The prototype robot “Whitegoat” is an eight-legged, radio-controlled walking robot. The possible applications of our robot might not be limited to medicine, however. We also plan to apply it to various other fields, considering its advantages in terms of practicality, mass productivity and mobility.
Cell Processing Robot
PI Takashi K. SAITO, Associate Professor: curriculum vitae
Researchmap.jp "Takashi K. SAITO"
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